| Date | Location | Result | |
| 3/4/11 | Hope College, DeVos Fieldhouse | Hope College 77, DePauw University 65 | Box score |
| 2/27/11 | Jackson, Miss. (The Hangar Dome) | DePauw University 80, Hendrix College 71 | Box score |
| 2/26/11 | Jackson, Miss. (The Hangar Dome) | DePauw University 73, Trinity University 53 | Box score |
| 2/25/11 | Jackson, Miss. (The Hangar Dome) | DePauw University 67, Colorado College 42 | Box score |
| 2/20/11 | Mallory Gymnasium | DePauw University 75, Rhodes College 46 | Box score |
| 2/18/11 | Birmingham, Ala. (Bill Battle Coliseum) | DePauw University 75, Birmingham-Southern 65 | Box score |
| 2/13/11 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 87, Sewanee 41 | Box score |
| 2/11/11 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 86, Oglethorpe University 57 | Box score |
| 2/5/11 | Alumni Gymnasium, Danville, Ky. | DePauw University 67, Centre College 54 | Box score |
| 1/30/11 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 69, Austin College 30 | Box score |
| 1/28/11 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 90, Colorado College 60 | Box score |
| 01/22/11 | Georgetown, TX | DePauw University 77, Southwestern (Tex.) 47 | Box score |
| 01/21/11 | Trinity University, Sams Gymnasium | Trinity University 68, DePauw University 59 | Box score |
| 1/16/11 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 85, Hendrix College 68 | Box score |
| 1/14/11 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 71, Millsaps College 41 | Box score |
| 01/09/11 | Sewanee, TN | DePauw University 87, Sewanee 31 | Box score |
| 01/08/11 | Dorough Field House/Atlanta, Ga. | DePauw University 71, Oglethorpe University 48 | Box score |
| 1/2/11 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 77, Centre College 57 | Box score |
| 12/29/10 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 85, John Carroll 47 | Box score |
| 12/28/10 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 60, Rose-Hulman 33 | Box score |
| 12/21/10 | Alma, MI {Art Smith Arena} | DePauw University 84, Alma College 58 | Box score |
| 12/18/10 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 66, Elmhurst College 47 | Box score |
| 12/8/10 | Griswold Center in Decatur, Illinois | Millikin University 65, DePauw University 59 | Box score |
| 12/5/10 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 68, Rhodes College 37 | Box score |
| 12/3/10 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 68, Birmingham-Southern 39 | Box score |
| 11/27/10 | Thousand Oaks, CA (Gilbert Arena) | DePauw University 63, Redlands 38 | Box score |
| 11/26/10 | Thousand Oaks, CA (Gilbert Arena) | DePauw University 76, La Verne 61 | Box score |
| 11/21/10 | Neal Fieldhouse; Greencastle, Indiana | Washington University 58, DePauw University 56 | Box score |
| 11/19/10 | Neal Fieldhouse; Greencastle, Indiana | DePauw University 77, Illinois Wesleyan University 65 | Box score |